Obesity

Effect of cannabis and subproducts on anthropometric measures: a systematic review and meta-analysis

Int J Obes (Lond)Published Systematic review and meta-analysis of randomised trials

Authors' conclusion

These findings suggest that cannabis and subproducts could be considered adjuncts in obesity treatment by helping to reduce relevant anthropometric measurements.

Study context

Population
RCTs evaluating cannabis and/or subproducts use and changes in anthropometric measures; MEDLINE, Embase, Cochrane Library and Web of Science searched until March 2023
Comparison
Cannabis and/or subproducts use vs control
Outcome
Changes in body weight, BMI and waist circumference (WC)
Methodological detailsSystematic search of MEDLINE, Embase, Cochrane Library and Web of Science until March 2023; meta-analysis in R software
  • Systematic search of MEDLINE, Embase, Cochrane Library and Web of Science until March 2023; meta-analysis in R software

Pooled result

As reported in the abstract

CannabisMean difference (95% CI)
WC
−2.19(−4.44 to 0.06)
Weight reduced with cannabis
weight reduction 1.87 kg (95% CI −3.71 to −0.03)

Further pooled results

Body mass index (BMI), subgroup with longer follow-up

Longer follow-up associated with more pronounced BMI reduction (MD)
−1.10 (95% CI: −2.23 to 0.03)
  • Subgroup analysis

Body fat, cannabinoid CB1

Cannabinoid CB1 exhibited an increase in body fat (MD)
1.70 (95% CI: 0.66-2.74)

Original publication

Effect of cannabis and subproducts on anthropometric measures: a systematic review and meta-analysis. Int J Obes (Lond). Published 7 November 2023. doi:10.1038/s41366-023-01399-x

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