Effect of Arterialization on Venous Blood Glucose Concentrations and Implications for Observed Continuous Glucose Monitoring Accuracy
Authors' conclusion
Heating of the arm led to a small increase in venous glucose concentrations, but venous concentrations did not reach the level of capillary glucose concentrations. CGM accuracy observed in this study varied depending on the selected comparator data.
Study context
- Population
- Participants undergoing three 6-h glucose challenges with venous and capillary sampling every 15 min on both arms and continuous glucose monitoring (CGM) sensors on each upper arm
- Participants
- 20 participants
- Comparison
- Heated vs nonheated arm
- Outcome
- Venous glucose concentrations with heating
Main finding
As reported in the abstract
Median increase in venous glucose with arm heating
+1.4%
Median capillary to venous difference, nonheated arm
+5.9%
Median capillary to venous difference, heated arm
+4.2%
Further findings
- Observed CGM accuracy affected by selection of heated venous, nonheated venous, or capillary glucose as comparator
- Heating effect more pronounced with rapidly decreasing glucose
Safety
- Skin temperatures did not exceed
- 40°C (104°F)
- Adverse events or protocol deviations associated with the heating pad
- 0
Original publication
Effect of Arterialization on Venous Blood Glucose Concentrations and Implications for Observed Continuous Glucose Monitoring Accuracy. Diabetes Technol Ther. Published 13 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →