Early vascular aging as an index of cardiovascular risk in healthy adults: confirmatory factor analysis from the EVasCu study
Authors' conclusion
The EVA index proved to be an adequate model to classify patients into different cardiovascular risk groups, which could be valuable in guiding future preventive and therapeutic interventions.
Study context
- Population
- Healthy adults (EVasCu study)
- Participants
- 390 adults
- Exposure
- Healthy vascular aging (HVA) vs early vascular aging (EVA)
- Outcome
- Construct validity of a single-factor model of EVA based on vascular, clinical and biochemical parameters; classification into CV risk groups (HVA, EVA)
Methodological detailsconfirmatory factor analysis, unsupervised clustering (K-means and hierarchical)
- Confirmatory factor analysis
- Unsupervised clustering (K-means and hierarchical)
Main finding
As reported in the abstract
Optimal number of risk groups to separate patients (HVA and EVA)
K = 2
Observational data: associations, not effects.
Original publication
Early vascular aging as an index of cardiovascular risk in healthy adults: confirmatory factor analysis from the EVasCu study. Cardiovasc Diabetol. Published 17 August 2023. doi:10. 1186/ s12933-023-01947-9
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