Early vascular aging as an index of cardiovascular risk in healthy adults: confirmatory factor analysis from the EVasCu study

Cardiovasc DiabetolPublished Cross-sectional study

Authors' conclusion

The EVA index proved to be an adequate model to classify patients into different cardiovascular risk groups, which could be valuable in guiding future preventive and therapeutic interventions.

Study context

Population
Healthy adults (EVasCu study)
Participants
390 adults
Exposure
Healthy vascular aging (HVA) vs early vascular aging (EVA)
Outcome
Construct validity of a single-factor model of EVA based on vascular, clinical and biochemical parameters; classification into CV risk groups (HVA, EVA)
Methodological detailsconfirmatory factor analysis, unsupervised clustering (K-means and hierarchical)
  • Confirmatory factor analysis
  • Unsupervised clustering (K-means and hierarchical)

Main finding

As reported in the abstract

Optimal number of risk groups to separate patients (HVA and EVA)

K = 2

Observational data: associations, not effects.

Original publication

Early vascular aging as an index of cardiovascular risk in healthy adults: confirmatory factor analysis from the EVasCu study. Cardiovasc Diabetol. Published 17 August 2023. doi:10.1186/s12933-023-01947-9

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