Gestational diabetes & diabetes in pregnancy
Early screening and diagnosis of gestational diabetes mellitus (GDM) and its impact on perinatal outcomes
Authors' conclusion
Fasting glucose levels modified the effects of early treatment of GDM where a higher-FBG with immediate treatment appears to reduce perinatal complications, but treating women with lower-FBG early has no benefits.
Study context
- Population
- Women with GDM, categorised by weeks of gestation at diagnosis
- Participants
- 3,494 women
- Exposure
- Early GDM diagnosis vs routine GDM diagnosis
- Outcome
- LGA and SGA
Main finding
As reported in the abstract
- RR for large for gestational age (LGA) and small for gestational age (SGA) similar for early vs routine diagnosis
- RR for LGA and SGA similar for immediate vs delayed treatment
- Adjusted for confounding
Observational data: associations, not effects.
Further findings
| Outcome | RR (95 % CI) | |
|---|---|---|
| Newborn respiratory distress (higher-FBG subgroup)Higher-FBG immediatevs Higher-FBG delayed | 0.52 (0.34–0.81) | |
| Emergency caesarean (higher-FBG subgroup)Higher-FBG immediatevs Higher-FBG delayed | 0.55 (0.34–0.88) | |
| 0.20.5125Relative risk (log scale) |
Lower-FBG subgroup
- Among lower-FBG, no such benefits seen
Original publication
Early screening and diagnosis of gestational diabetes mellitus (GDM) and its impact on perinatal outcomes. Diabetes Res Clin Pract. Published 19 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →