Duration of physical activity required to Ameliorate hyperglycemia without causing hypoglycemia in type 1 diabetes: A T1DEXI adults and pediatric cohort analyses
Authors' conclusion
Time-limited activity is an effective means of restoring TIR when hyperglycemia exists in adolescents and adults with T1D.
Study context
- Population
- Adults (28-day observation) and adolescents (10-day observation) with T1D, CGM and activity data; activities 10–60 min with starting glucose 181–300 mg/dL and no meals during activity1,902 activities
- Exposure
- Starting glucose categories
- Outcome
- Activity duration required to lower glucose from >180 mg/dL to within TIR (70-180 mg/dL)
Methodological detailsKaplan-Meier analysis
- Kaplan-Meier analysis
Main finding
As reported in the abstract
Estimated activity duration for 50 % chance of reaching TIR
181-199 mg/dL
15
min
200-224 mg/dL
31
min
225-249 mg/dL
59
min
250-300 mg/dL
≥ 60
min
Observational data: associations, not effects.
Further findings
Activity duration requirements by pre-activity glucose trend and bolus insulin on board
- Duration requirements increased irrespective of starting glucose when glucose trending upwards before activity and with zero bolus insulin on board at start
Adults vs adolescents
- Adult and adolescent results were similar
Safety
Hypoglycemia in the hour after activity
- Incidence of hypoglycemia
- 0-11 %
Original publication
Duration of physical activity required to Ameliorate hyperglycemia without causing hypoglycemia in type 1 diabetes: A T1DEXI adults and pediatric cohort analyses. Diabetes Res Clin Pract. Published 27 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →