Differential Ultrasound Rates Mirror Sex Disparities in Thyroid Cancer
Authors' conclusion
Sex disparities in thyroid ultrasound rates are stark and are a likely driver of sex disparities in thyroid cancer incidence.
Study context
- Population
- Kaiser Permanente of Washington enrollees aged ≥18 years who underwent thyroid US, 1997–201978% females
- Participants
- 33,589 participants
- Exposure
- Males vs females
- Outcome
- Annual US, FNAB and cancer incidence rates; proportion of US requiring FNAB; cancer diagnoses per FNAB
- Follow-up
- 1997–2019
Methodological detailslongitudinal, integrated health system
- Longitudinal
- Integrated health system
Main finding
As reported in the abstract
US rates per 100,000 covered lives · 1997 to 2019
Males
111.11-490.97
per 100,000 covered lives
Females
382.27-1331.14
per 100,000 covered lives
Observational data: associations, not effects.
Further findings
| Outcome | Adj rate ratio (CI) | |
|---|---|---|
| FNAB per USAdjusted for patient and sociodemographic characteristics | 1.06 (1.01–1.11) | |
| 0.512Adj rate ratio (log scale) |
| Outcome | Males | Females | P value |
|---|---|---|---|
| FNAB rates per 100,000 · 1997 to 2019 | 58.38-189.13 per 100,000 | 174.09-430.37 per 100,000 | |
| Cancer incidence per FNAB | 0.06 | 0.06 | P = 0.4 |
Fine needle aspiration biopsy (FNAB) per US
- FNAB rates per US changed little over time
Cancer incidence per FNAB
- Cancer incidence higher in females over the study period
Original publication
Differential Ultrasound Rates Mirror Sex Disparities in Thyroid Cancer. Thyroid. Published 28 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →