Type 2 & other diabetes

Dietary Factors and All-Cause Mortality in Individuals With Type 2 Diabetes: A Systematic Review and Meta-analysis of Prospective Observational Studies

Diabetes CarePublished Systematic review and meta-analysis of prospective observational studies

Authors' conclusion

Higher intake of fish, whole grain, fiber, and n-3 polyunsaturated fatty acids were inversely associated with all-cause mortality in individuals with type 2 diabetes. There is limited evidence for other dietary factors, and, thus, more research is needed.

Study context

Population
Individuals with T2D; PubMed and Web of Science searched until June 2022107 studies
Comparison
Higher vs lower intake of dietary factors
Outcome
All-cause mortality

Pooled result

As reported in the abstract

All-cause mortality by dietary factor (summary RR)
Fish, per serving/week (moderate certainty; n = 6 studies)
0.95; 95% CI 0.92, 0.99
Whole grain, per 20 g/day (moderate certainty; n = 2)
0.84; 95% CI 0.71, 0.99
Fiber, per 5 g/day (moderate certainty; n = 3)
0.86; 95% CI 0.81, 0.91
n-3 polyunsaturated fatty acids, per 0.1 g/day (moderate certainty; n = 2)
0.87; 95% CI 0.82, 0.92
Vegetables, per 100 g/day (low certainty; n = 2)
0.88; 95% CI 0.82, 0.94
Plant protein, per 10 g/day (low certainty; n = 3)
0.91; 95% CI 0.87, 0.96
Eggs, per 10 g/day (low certainty; n = 7)
1.05; 95% CI 1.03, 1.08
Cholesterol, per 300 mg/day (low certainty; n = 2)
1.19; 95% CI 1.13, 1.26

Original publication

Dietary Factors and All-Cause Mortality in Individuals With Type 2 Diabetes: A Systematic Review and Meta-analysis of Prospective Observational Studies. Diabetes Care. Published 26 January 2023. doi:10.2337/dc22-1018

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