Diabetes remission strategies in published and ongoing randomized controlled trials: A scoping review of present and emerging intervention types, remission definitions, and weight loss targets
Authors' conclusion
Evidence on remission strategies with recognized definitions will nearly double, largely through behavioural interventions retaining a weight loss focus.
Study context
- Population
- Trials on remission in adults with T2D; MEDLINE, Embase, Cochrane Register and major trial registries searched through January 2026
- Participants
- 71 vs 52
- Comparison
- Published vs ongoing trials
- Publishedn = 71reference
- Ongoingn = 52
Methodological detailstwo independent reviewers
- Two independent reviewers
Primary result
As reported in the abstract
Trial characteristics: intervention type, remission definition, weight loss targets
- Published trials: surgical interventions
- 41%
- Published trials: health behavioural interventions
- 32%
- Published trials: combination interventions
- 10%
- Published trials: pharmacological interventions
- 17%
- Ongoing trials: health behavioural interventions
- 54%
- Recognized remission definition, ongoing vs published
- n = 46, 88% vs n = 51, 72%
- Remission as primary outcome, ongoing vs published
- 54% vs 41%
- Weight loss as a target, ongoing vs published
- 89% vs 88%
Original publication
Diabetes remission strategies in published and ongoing randomized controlled trials: A scoping review of present and emerging intervention types, remission definitions, and weight loss targets. Diabetes Res Clin Pract. Published 12 August 2026. doi:10. 1016/ j. diabres. 2026. 113466
Composed by AI from the published abstract and checked against it. How Briefs are made →