Diabetes, Atherosclerosis, and Stenosis by AI
Authors' conclusion
Patients with diabetes and nonobstructive stenosis had an association to similar APCs as patients without diabetes who had obstructive stenosis. Among patients with nonobstructive disease, patients with diabetes had more total PV and NCP.
Study context
- Population
- Patients from the CREDENCE trial referred for invasive coronary angiography with coronary computed tomographic angiography (CCTA); lesions classified as obstructive (≥50% stenosed) or nonobstructive by quantitative coronary angiography
- Participants
- 303 patients
- Comparison
- Patients with vs without diabetes, by obstructive vs nonobstructive stenosis
- Diabetesn = 95
Methodological detailsretrospective, blinded core laboratory analysis
- Retrospective
- Blinded core laboratory analysis
Primary result
As reported in the abstract
- Nonobstructive disease: greater plaque volume (PV) with diabetes vs without
- P = 0.02
- Nonobstructive disease: greater percentage of atheroma volume (PAV) with diabetes vs without
- P = 0.02
- Nonobstructive disease: greater noncalcified plaque (NCP) with diabetes vs without
- P = 0.03
- Nonobstructive disease: greater PAV NCP with diabetes vs without
- P = 0.02
- Nonobstructive disease: more diseased vessels with diabetes vs without
- P = 0.03
- Nonobstructive disease: greater maximum stenosis with diabetes vs without
- P = 0.02
Further findings
- Lesions in cohort with diabetes
- 117
- Obstructive among these lesions
- 58.1%
Original publication
Diabetes, Atherosclerosis, and Stenosis by AI. Diabetes Care. Published 26 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →