Diabetes and pancreatic cancer risk in a multiracial cohort
Main finding · Pancreatic cancer riskResult — go to the resultHazard ratio 1.54 CI 1.16–2.05Authors' conclusion
Diabetes increases pancreatic cancer risk similarly among African Americans and Whites in this Southern U.S.
Study context
- Population
- Mostly low-income African American and White participants aged 40–79 years, Southern Community Cohort Study, follow-up 2002–2015265 incident cases
- Participants
- 73,378 participants
- Exposure
- Diabetes vs no diabetes
- Diabetesn = 15,913
- Outcome
- Pancreatic cancer incidence
- Follow-up
- 2002-2015
Methodological detailsmultiracial cohort, multivariable Cox analysis with age as timescale
- Multiracial cohort
- Multivariable Cox analysis with age as timescale
Main finding
Pancreatic cancer risk
Hazard ratio
1.54
CI 1.16–2.05
Diabetesvs No diabetes
HR 1.54 (CI 1.16–2.05)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Pancreatic cancer risk, African Americans vs WhitesAfrican Americansvs Whites | 1.40 (1.05–1.87) | |
| Pancreatic cancer risk, African Americans vs WhitesAfrican Americansvs WhitesAdjusted for diabetes | 1.36 (1.02–1.81) | |
| 0.512Hazard ratio (log scale) |
Pancreatic cancer risk with diabetes, by race
- African Americans: HR
- 1.51 (1.08-2.11) (CI)
- Whites: HR
- 1.78 (1.00-3.16) (CI)
- Similar increases among African Americans and Whites
Pancreatic cancer risk by diabetes duration
- <5 years: HR
- 1.39 (0.91-2.11)
- 5-9 years: HR
- 2.31 (1.51-3.54)
- 10+ years: HR
- 1.23 (0.80-1.89)
- No trend in risk for diabetes duration
Other pancreatic cancer risk factors by diabetes status
- Effect sizes similar by diabetes status; stronger association with low BMI among those with diabetes
Original publication
Diabetes and pancreatic cancer risk in a multiracial cohort. Diabet Med. Published 15 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →