Type 1 diabetes

Development and validation of a nomogram to predict diabetes ketoacidosis resolution time in a tertiary care hospital in the United Arab Emirates

Diabetes Res Clin PractPublished Retrospective cohort study

Authors' conclusion

An effective nomogram was established for estimating the likelihood of DRT ≥ 24 h, facilitating better resource allocation and personalized treatment strategy.

Study context

Population
Adults with diabetes ketoacidosis (DKA) admitted to Tawam Hospital, United Arab Emirates, January 2017–October 2022; average age 34 years, 54 % female
Participants
394 adults
Outcome
Prediction of prolonged DKA resolution time (DRT ≥ 24 h): discrimination (C-index) and calibration (calibration plot, Brier score)
Methodological detailsprediction model development and validation, single-centre, logistic regression stepwise model, nomogram
  • Prediction model development and validation
  • Single-centre
  • Logistic regression stepwise model
  • Nomogram

Main finding

As reported in the abstract

Nomogram performance for predicting DRT ≥ 24 h

C-index (good discrimination)

0.76

Brier score (good calibration and predictive accuracy)

0.17

Observational data: associations, not effects.

Original publication

Development and validation of a nomogram to predict diabetes ketoacidosis resolution time in a tertiary care hospital in the United Arab Emirates. Diabetes Res Clin Pract. Published 2 July 2024. doi:10.1016/j.diabres.2024.111763

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