Gestational diabetes & diabetes in pregnancy
Determinants of progression of diabetic retinopathy in pregnancy
Main finding · DR progressionResult — go to the resultOdds ratio 9.88 CI 4.43–22.07Authors' conclusion
Women without DR at baseline are unlikely to progress to more severe forms of DR and usually do not require treatment. The presence of DR at baseline screening during pregnancy is a strong predictor of DR progression during pregnancy.
Study context
- Population
- Pregnancies of women with type 1 or 2 DM, King Edward Memorial Hospital, Western Australia, June 2020–July 2023; Diabetic retinopathy (DR) screening by retinal imaging in first trimester and/or at 28–32 weeks gestation
- Participants
- 367 pregnancies
- Exposure
- Baseline DR vs no baseline DR
- Baseline DRn = 121
- Outcome
- DR progression in pregnancy
Methodological detailssingle-centre
- Single-centre
Main finding
DR progression
Odds ratio
9.88
CI 4.43–22.07
P < 0.001
Events by group
Baseline DRvs No baseline DR
OR 9.88 (CI 4.43–22.07); P < 0.001
As reported in the abstract
- DR progression, all pregnancies
- 62 (17 %)
Observational data: associations, not effects.
Further findings
DR at baseline
- Pregnancies with DR at baseline
- 121 (33 %)
Severity of new DR in women without baseline DR
- Progressed to more than moderate non-proliferative DR
- 0
Original publication
Determinants of progression of diabetic retinopathy in pregnancy. Diabetes Res Clin Pract. Published 14 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →