Obesity

Delay discounting and nucleus accumbens functional connectivity are related to weight status in adolescents from the Adolescent Brain and Cognitive Development (ABCD) study

Pediatr ObesPublished Longitudinal cohort study

Authors' conclusion

Delay discounting and nucleus accumbens functional connectivity are independently related to weight status in a large sample of early adolescents. A better understanding of the relationship between reward and overeating behaviours may better inform obesity interventions.

Study context

Population
10–12-year-olds from the Adolescent Brain and Cognitive Development (ABCD) Study1,817 with connectivity data
Participants
3,819 participants
Outcome
Relationships between weight status (BMIz, WHtRz), monetary delay-discounting performance and nucleus accumbens functional connectivity
Methodological detailssecondary analysis of the ABCD Study, multilevel longitudinal linear modelling
  • Secondary analysis of the ABCD Study
  • Multilevel longitudinal linear modelling

Main finding

As reported in the abstract

  • Greater discounting associated with higher BMIz and WHtRz

Observational data: associations, not effects.

Further findings

Nucleus accumbens functional connectivity and BMIz

Nucleus accumbens connectivity to cingulo-opercular, dorsal attention, fronto-parietal, salience and ventral attention networks predictive of BMIz
Nucleus accumbens connectivity did not mediate the delay discounting–BMIz association
  • N = 1817

Original publication

Delay discounting and nucleus accumbens functional connectivity are related to weight status in adolescents from the ABCD study. Pediatr Obes. Published 17 September 2024. doi:10.1111/ijpo.13173

Composed by AI from the published abstract and checked against it. How Briefs are made →

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