Diabetes technology

Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes

J Clin Endocrinol MetabPublished Cross-sectional study

Authors' conclusion

Our results contribute to the understanding of the physiological CGM range in more than 1000 participants without diabetes. These results are also important for clinicians to reference as CGM sensors become more widely accessible to people without known diabetes.

Study context

Population
Community-dwelling adults of the Framingham Heart Study who wore a blinded Dexcom G6 Pro continuous glucose monitor (CGM) for ≥7 complete days; normoglycemic: mean age 58.5 years, 64.5% women, 93.3% non-Hispanic White
Participants
560 / 463 / 152
Exposure
CGM metrics across glycemic status: normoglycemia, prediabetes, diabetes
  • Normoglycemian = 560
  • Prediabetesn = 463
  • Diabetesn = 152
Outcome
CGM metrics incl. mean glucose and time spent in glucose ranges
Methodological detailswithin the Framingham Heart Study prospective cohort, blinded CGM (Dexcom G6 Pro) ≥7 complete days
  • Within the Framingham Heart Study prospective cohort
  • Blinded CGM (Dexcom G6 Pro) ≥7 complete days

Main finding

As reported in the abstract

CGM time in 70 to 140 mg/dL range

Observational data: associations, not effects.

Further findings

OutcomeValues
CGM time >180 mg/dL, normoglycemic participantsOn averageNormoglycemic mean 1.2% time · time per day more than 15 minutes/day
CGM time >140 mg/dL, normoglycemic participantsNormoglycemic 12.1% time · time per day ≈3 hours/day

Original publication

Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes. J Clin Endocrinol Metab. Published 11 September 2024. doi:10.1210/clinem/dgae626

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