Diabetes technology

Cost‐effectiveness of the tandem t: Slim X2 with control‐IQ technology automated insulin delivery system in children and adolescents with type 1 diabetes in Sweden

Diabet MedPublished Cost-effectiveness analysis

Authors' conclusion

Initiation of CIQ use in children with type 1 diabetes is cost-saving, besides previously shown improved glycaemic control, and increased quality of life. Further investigations are needed to more fully elucidate the cost-effectiveness of these technologies in different countries with existing differences in payment models.

Study context

Population
Children with T1D in Sweden
Participants
84 children
Exposure
CIQ vs MDI or continuous subcutaneous insulin infusion (CSII), in conjunction with CGM
  • CIQn = 37
  • MDIn = 19reference
  • CSIIn = 28reference
Outcome
Quality adjusted life years (QALYs), cost per QALY and ICER
Follow-up
10, 20 and 30-year time horizons
Methodological detailsMarkov model, four-state Markov model, probabilistic sensitivity analyses, clinical input from retrospective observational study, Data sources: retrospective observational study, local diabetes supply companies and government agencies, published literature
  • Markov model
  • Four-state Markov model
  • Probabilistic sensitivity analyses
  • Clinical input from retrospective observational study
  • Data sources: retrospective observational study, local diabetes supply companies and government agencies, published literature

Main finding

As reported in the abstract

ICER · 10, 20 and 30 years
CIQ vs MDI
10-year incremental cost-effectiveness ratio (ICER) −88,010.37 SEK
CIQ vs CSII
10-year ICER −91,723.92 SEK
CIQ vs MDI
20-year ICER −72,095.33 SEK
CIQ vs CSII
20-year ICER −87,707.79 SEK
CIQ vs MDI
30-year ICER −65,573.01 SEK
CIQ vs CSII
30-year ICER −85,495.68 SEK

Observational data: associations, not effects.

Further findings

Probabilistic sensitivity analyses

Probabilistic sensitivity analyses (PSA) confirmed CIQ was less costly vs MDI and CSII

Original publication

Cost‐effectiveness of the tandem t: Slim X2 with control‐IQ technology automated insulin delivery system in children and adolescents with type 1 diabetes in Sweden. Diabet Med. Published 6 September 2024. doi:10.1111/dme.15432

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