Extended use of real‐time continuous glucose monitoring in adults with insulin‐requiring type 2 diabetes: Results from the first 26 weeks of the 2GO‐CGM trial
Primary result · Time in range (3.9-10.0 mmol/L), baseline-adjusted meanResult — go to the resultDifference 15 % 95% CI 10–20Authors' conclusion
Use of rtCGM demonstrates safe and sustained glycaemic improvement in rtCGM use with insulin-requiring type 2 diabetes during the first 26 weeks of the 2GO-CGM study.
Study context
- Population
- Community-based adults with insulin-requiring T2D in New Zealand, within a supported specialist model of care; 53% indigenous Māori, 57% female, median age 53 (range 16–69) yearsall analysed
- Participants
- 67 adults
- Comparison
- Real-time continuous glucose monitoring (rtCGM) vs self-monitoring of blood glucose (SMBG)
Methodological detailsone-way crossover, waitlist-controlled, time-adjusted within-subject analysis
- One-way crossover
- Waitlist-controlled
- Time-adjusted within-subject analysis
Primary result
As reported in the abstract
Time in range (3.9-10.0 mmol/L), baseline-adjusted mean · 26 weeks
Difference
15 %
95% CI 10–20
P = <0.001
rtCGMvs SMBG
difference 15 % (95% CI 10–20); P = <0.001
Further findings
| Outcome | Difference (mmol/mol) (95% CI) | P value | |
|---|---|---|---|
| HbA1crtCGMvs SMBG[0.31%], 95% CI −0.86 to 0.24% | −3.4 (−9.4 to 2.7) | P = 0.27 | |
| −10−505Difference, mmol/mol (linear scale) |
HbA1c
- No evidence of a difference in HbA1c between rtCGM and SMBG
Safety
Withdrawal due to skin reactions to CGM device · phase 2
- Participant withdrew due to unmanageable skin reactions to the CGM device
- One participant
Severe hypoglycaemia or ketoacidosis · during the study
- There were no severe hypoglycaemia or ketoacidosis events in either group
Original publication
Extended use of real‐time continuous glucose monitoring in adults with insulin‐requiring type 2 diabetes: Results from the first 26 weeks of the 2GO‐CGM trial. Diabet Med. Published 18 March 2025. doi:10. 1111/ dme. 70025
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