Diabetes technology

Extended use of real‐time continuous glucose monitoring in adults with insulin‐requiring type 2 diabetes: Results from the first 26 weeks of the 2GO‐CGM trial

Diabet MedPublished Randomised controlled trial

Primary result · Time in range (3.9-10.0 mmol/L), baseline-adjusted meanResult — go to the resultDifference 15 % 95% CI 10–20

Authors' conclusion

Use of rtCGM demonstrates safe and sustained glycaemic improvement in rtCGM use with insulin-requiring type 2 diabetes during the first 26 weeks of the 2GO-CGM study.

Study context

Population
Community-based adults with insulin-requiring T2D in New Zealand, within a supported specialist model of care; 53% indigenous Māori, 57% female, median age 53 (range 16–69) yearsall analysed
Participants
67 adults
Comparison
Real-time continuous glucose monitoring (rtCGM) vs self-monitoring of blood glucose (SMBG)
Methodological detailsone-way crossover, waitlist-controlled, time-adjusted within-subject analysis
  • One-way crossover
  • Waitlist-controlled
  • Time-adjusted within-subject analysis

Primary result

As reported in the abstract

Time in range (3.9-10.0 mmol/L), baseline-adjusted mean · 26 weeks

Difference

15 %

95% CI 10–20

P = <0.001

rtCGMvs SMBG
difference 15 % (95% CI 10–20); P = <0.001

Further findings

OutcomeDifference (mmol/mol) (95% CI)P value
HbA1crtCGMvs SMBG[0.31%], 95% CI −0.86 to 0.24%−3.4 (−9.4 to 2.7)P = 0.27

HbA1c

No evidence of a difference in HbA1c between rtCGM and SMBG

Safety

Withdrawal due to skin reactions to CGM device · phase 2

Participant withdrew due to unmanageable skin reactions to the CGM device
One participant

Severe hypoglycaemia or ketoacidosis · during the study

There were no severe hypoglycaemia or ketoacidosis events in either group

Original publication

Extended use of real‐time continuous glucose monitoring in adults with insulin‐requiring type 2 diabetes: Results from the first 26 weeks of the 2GO‐CGM trial. Diabet Med. Published 18 March 2025. doi:10.1111/dme.70025

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