DASH4D diet for glycemic control and glucose variability in type 2 diabetes: a randomized crossover trial
Authors' conclusion
These results suggest that the DASH4D diet is a promising nutritional approach to substantially improve glycemic control in adults with type 2 diabetes.
Study context
- Population
- Participants with T2D
- Participants
- 89 participants
- Comparison
- DASH4D diet vs comparison diet, each with higher or lower sodium
- Primary endpoint
- Mean glucose; time in range (glucose 70–180 mg dl-1); CV, by 14 days of CGM during each feeding period
- Follow-up
- Each 5-week feeding period
Methodological detailsisocaloric diets
- Isocaloric diets
Primary result
As reported in the abstract
Mean glucose, TIR and CV
Mean difference (mean glucose)
−11.1 mg dl-1
P < 0.001
DASH4D
Mean difference (time in range)
+5.2 percentage points
P < 0.001
DASH4D
Secondary outcomes
Glucose SD and time with hyperglycemia (>180 and >250 mg dl-1)
- Lower with DASH4D diet
Time with hypoglycemia (<70 and <54 mg dl-1)
- Similar across diets
Safety
- Serious adverse events related to CGM or study diets
- 0
Original publication
DASH4D diet for glycemic control and glucose variability in type 2 diabetes: a randomized crossover trial. Nat Med. Published 5 August 2025. doi:10. 1038/ s41591-025-03823-3
Composed by AI from the published abstract and checked against it. How Briefs are made →