Adrenal disease

Cytological Assessment of Adrenal Tumours: Insights From 22‐Years Single Centre Experience

Clin Endocrinol (Oxf)Published Retrospective cohort study

Authors' conclusion

FNA of the adrenal glands is a safe, minimally invasive diagnostic procedure that can be useful in the assessment of adrenal lesions.

Study context

Population
Patients who underwent fine-needle aspiration (FNA) of adrenal glands at Karolinska University Hospital, Stockholm, Sweden, 2000–2022
Participants
241 patients251 FNAs
Exposure
Endoscopic ultrasound technique vs CT vs Transabdominal ultrasound technique
Outcome
Accuracy of the sample and complication rate
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Diagnostic FNA obtained (all patients)
90% (n = 217)
Sensitivity
93.8%
Specificity
96.7%

Observational data: associations, not effects.

Further findings

FNA findings and management

FNA consistent with adrenal metastases
52.7%
Adrenalectomy based on FNA results
13.6%
Benign findings managed conservatively
52.8%
Chemotherapy started for malignant findings
78.7%

Safety

Complication rate
7.9% (n = 20)

Original publication

Cytological Assessment of Adrenal Tumours: Insights From 22‐Years Single Centre Experience. Clin Endocrinol (Oxf). Published 23 April 2025. doi:10.1111/cen.15254

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