Cystic Fibrosis-Related Bone Disease in Youth: High-Risk Population With Low Screening Adherence
Authors' conclusion
Children with CF are experiencing fractures throughout their childhood and should undergo further evaluation for skeletal fragility, beginning with detailed fracture history. However, few children are completing DXA scans according to national guidelines.
Study context
- Population
- Children aged 8 to <18 years with cystic fibrosis (CF) seen in a pediatric CF clinic in 2022
- Participants
- 118 children
- Outcome
- Proportions of children who meet CFBD screening criteria, are ordered a DXA, and complete DXA screening
- Follow-up
- 2022
Methodological detailssingle-centre, chart review
- Single-centre
- Chart review
Main finding
As reported in the abstract
Met criteria for CFBD screening by DXA
Met criteria for CFBD screening by DXA
28%
Children meeting criteria who had a DXA ordered
1
Observational data: associations, not effects.
Further findings
Estimated cumulative incidence of childhood fracture (all patients followed in the clinic)
- Estimated cumulative incidence of childhood fracture
- 53%
Original publication
Cystic Fibrosis-Related Bone Disease in Youth: High-Risk Population With Low Screening Adherence. Endocr Pract. Published 2 April 2026. doi:10. 1016/ j. eprac. 2026. 03. 100
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