Osteoporosis, bone & mineral

Cystic Fibrosis-Related Bone Disease in Youth: High-Risk Population With Low Screening Adherence

Endocr PractPublished Retrospective cohort study

Authors' conclusion

Children with CF are experiencing fractures throughout their childhood and should undergo further evaluation for skeletal fragility, beginning with detailed fracture history. However, few children are completing DXA scans according to national guidelines.

Study context

Population
Children aged 8 to <18 years with cystic fibrosis (CF) seen in a pediatric CF clinic in 2022
Participants
118 children
Outcome
Proportions of children who meet CFBD screening criteria, are ordered a DXA, and complete DXA screening
Follow-up
2022
Methodological detailssingle-centre, chart review
  • Single-centre
  • Chart review

Main finding

As reported in the abstract

Met criteria for CFBD screening by DXA

Met criteria for CFBD screening by DXA

28%

Children meeting criteria who had a DXA ordered

1

Observational data: associations, not effects.

Further findings

Estimated cumulative incidence of childhood fracture (all patients followed in the clinic)

Estimated cumulative incidence of childhood fracture
53%

Original publication

Cystic Fibrosis-Related Bone Disease in Youth: High-Risk Population With Low Screening Adherence. Endocr Pract. Published 2 April 2026. doi:10.1016/j.eprac.2026.03.100

Composed by AI from the published abstract and checked against it. How Briefs are made →

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