Type 2 & other diabetes

Cost-effectiveness analysis of two interventions to promote physical activity in a multiethnic population at high risk of diabetes: an economic evaluation of the 48-month PROPELS randomized controlled trial

BMJ Open Diabetes Res CarePublished Cost-effectiveness analysis

Primary resultResult — go to the resultICER £49 273 per QALY gained

Authors' conclusion

We found that neither WA nor WA+ was cost-effective at a limit of £20 000 per QALY gained. Our threshold analysis showed that interventions to increase step count can be cost-effective at this limit if they achieve greater long-term maintenance of effect.

Study context

Population
Multiethnic population at high risk of T2D (PROPELS trial data)
Comparison
Walking Away and Walking Away Plus vs usual care
Primary endpoint
Lifetime costs, lifetime quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICERs) vs usual care, compared with NICE willingness-to-pay of £20 000-£30 000 per QALY gained
Follow-up
Lifetime
Methodological detailseconomic evaluation of the PROPELS randomised controlled trial, model-based (adapted School for Public Health Research diabetes prevention model), lifetime horizon, scenario analyses, threshold analysis
  • Economic evaluation of the PROPELS randomised controlled trial
  • Model-based (adapted School for Public Health Research diabetes prevention model)
  • Lifetime horizon
  • Scenario analyses
  • Threshold analysis

Primary result

As reported in the abstract

ICER

£49 273 per QALY gained

By group

Usual care

£22 598

Walking Away (WA)

£23 018

WA+

£22 945

Further findings

Scenario analyses

In no scenario did WA or WA+ have an ICER below £20 000 per QALY gained

Threshold analysis · 4 years

Physical activity (PA) intervention costing the same as WA+ would have ICER below £20 000/QALY with step-count increase 100% maintained at 4 years
500 steps per day

Original publication

Cost-effectiveness analysis of two interventions to promote physical activity in a multiethnic population at high risk of diabetes: an economic evaluation of the 48-month PROPELS randomized controlled trial. BMJ Open Diabetes Res Care. Published 12 March 2024. doi:10.1136/bmjdrc-2023-003516

Composed by AI from the published abstract and checked against it. How Briefs are made →

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