Corneal Confocal Microscopy Abnormalities in Children and Adolescents With Type 1 Diabetes
Authors' conclusion
CCM was able to detect corneal nerve loss in children with and without abnormalities in TDT and NCS.
Study context
- Population
- Children and adolescents with T1D without neuropathic symptoms or signs, and healthy controls
- Exposure
- Corneal confocal microscopy (CCM) vs thermal detection thresholds (TDT) testing and nerve conduction studies (NCS) for detecting neuropathy in children with T1D
- Outcome
- Neuropathy abnormalities in T1DM by test
Main finding
As reported in the abstract
- NCS abnormalities in T1DM
- 18 (35%)
- Abnormal TDT (small fiber dysfunction) in T1DM
- 13 (25.5%)
- CCM abnormalities in T1DM
- 25 (49%)
- CCM abnormal among T1DM with abnormal TDT
- 12/13, 92%
- CCM abnormal among T1DM with abnormal NCS
- 16/18, 88%
- CCM abnormal among T1DM with normal TDT
- 13/38 (34%)
- CCM abnormal among T1DM with normal NCS
- 9/33 (27%)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Corneal Confocal Microscopy Abnormalities in Children and Adolescents With Type 1 Diabetes. Endocr Pract. Published 19 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →