Gestational diabetes & diabetes in pregnancy
Continuous Glucose Monitoring Metrics in Women with Type 2 Diabetes in Pregnancy: The TIMELY Observational Cohort Study
Authors' conclusion
Several glycemic metrics, including TIRp and mean glucose, were associated with LGA. Higher glucose levels from 12 weeks onward were seen in mothers of LGA infants.
Study context
- Population
- Pregnant women with T2D enrolled before 26 weeks of gestation, 3 diabetes in pregnancy clinics; mean enrolment 16 weeks, 83% non-European ethnicity
- Participants
- 50 women
- Outcome
- CGM metrics across pregnancy
- Follow-up
- Across pregnancy
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Mean TIRp (3.5-7.8 mmol/L)
73.0%
Mean TARp
25.6%
Mean time below range
1.5%
Mean glucose, mean (SD)
6.8 (1.0) mmol/L
Observational data: associations, not effects.
Further findings
LGA by TIRp category
P = 0.02
| Outcome | OR (CI) | P value | |
|---|---|---|---|
| LGA per 5% improvement in TIRpReduced LGA by 28% | 0.72 (0.54–0.90) | P = 0.009 | |
| 0.512Odds ratio (log scale) |
Other associations
- Wore continuous glucose monitoring (CGM) >80% of the time from enrolment
- 74%
- Mean glucose significantly higher in those with an large-for-gestational-age (LGA) infant from 12 weeks onward
- TARp >30% significantly associated with composite neonatal outcome
- >20% TARp overnight significantly associated with LGA
- Diabetes distress at enrolment associated with significantly lower TIRp and higher mean glucose throughout pregnancy
Original publication
Continuous Glucose Monitoring Metrics in Women with Type 2 Diabetes in Pregnancy: The TIMELY Observational Cohort Study. Diabetes Technol Ther. Published 21 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →