Continuous Glucose Monitoring-Derived Glycemic Profiles and Correlates in Young Adults Ages 18 to 26 Years
Authors' conclusion
CGM revealed sex differences in young adults-males exhibited higher mean glucose and excursions-while both sexes maintained normoglycemic patterns. Age, BMI, and PA were linked to variability indices. Findings provide CGM reference data for young adults and highlight the importance of biological and behavioral factors in glycemic regulation.
Study context
- Population
- Young adults aged 18–26 years without diabetes; median age 21 years, body mass index (BMI) 23 kg/m² [21–25]; 72% female; 72% non-White≥48hr of continuous glucose monitoring (CGM) data
- Participants
- 105 adults
- Exposure
- Males vs females; associations with age, BMI and physical activity (PA)
- Outcome
- Mean sensor glucose
Methodological detailsfree-living conditions, unmasked Dexcom G7 CGM for up to 10 days
- Free-living conditions
- Unmasked Dexcom G7 CGM for up to 10 days
Main finding
As reported in the abstract
P < 0.01
Observational data: associations, not effects.
Further findings
Median
| Outcome | Males | Females | P value |
|---|---|---|---|
| eA1cHigher in males | 5.4 (IQR 5.2–5.8) | 5.2 (IQR 5.1–5.4) | P < 0.01 |
| Glucose AUCHigher in males | 110 (IQR 102–119) | 103 (IQR 99–108) | P = 0.01 |
| Daily episodes >140 mg/dLHigher in males | 1.6 (IQR 1.0–2.6) | 1.3 (IQR 0.7–2.0) | P = 0.03 |
Correlates of glycemic variability
- Age vs CV, r
- .20 (P = .04)
- BMI vs CV, r
- −.35 (P < .001)
- BMI vs MAGE, r
- −.35 (P < .001)
- BMI vs MODD, r
- −.27 (P < .001)
- PA modestly associated with reduced glycemic burden
Original publication
Continuous Glucose Monitoring-Derived Glycemic Profiles and Correlates in Young Adults Ages 18 to 26 Years. J Diabetes Sci Technol. Published 7 December 2025. doi:10.
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