Type 2 & other diabetes

Continuity of Medication Use by US Adults With Diabetes, 2005-2019

JAMA Netw OpenPublished Serial cross-sectional study

Authors' conclusion

This study found that a mean of 19.5% of participants did not maintain continuity in use of glucose-lowering medication, with recent decreases, while a mean of 17.1% and 43.2% of participants did not maintain continuity of use of blood pressure- or lipid-lowering medications, respectively.

Study context

Population
US adults with diagnosed diabetes in both years, participating in all Medical Expenditure Panel Survey (MEPS) survey rounds, 2005–2006 to 2018–2019 panels
Participants
15,237 adults
Exposure
Trends in medication continuity, 2005-2006 to 2018-2019 MEPS panels
Outcome
Longitudinal use (continued, none, inconsistent, new) of glucose-, blood pressure- and lipid-lowering medications
Follow-up
Over 2 years
Methodological detailspopulation-weighted, nationally representative, 2-year longitudinal follow-up, Data analyzed August 2021 to November 2022
  • Population-weighted, nationally representative
  • 2-year longitudinal follow-up
  • Data analyzed August 2021 to November 2022

Main finding

As reported in the abstract

Did not maintain continuity of medication use · both years of follow-up

Glucose-lowering, mean

19.5%

95% CI 18.6%–20.3%

Blood pressure-lowering, mean

17.1%

95% CI 16.2%–18.1%

Lipid-lowering, mean

43.3%

95% CI 42.2%–44.3%

Observational data: associations, not effects.

Further findings

Trends in glucose-lowering medication use · 2005-2006 to 2018-2019

Continued use, 2005-2006
84.5% (95% CI 81.8%-87.3%)
Continued use, 2018-2019
77.4% (95% CI 74.8%-80.1%)
Inconsistent use, 2005-2006
3.3% (95% CI 1.9%-4.7%)
Inconsistent use, 2018-2019
7.1% (95% CI 5.6%-8.6%)
No use, 2005-2006
8.1% (95% CI 6.0%-10.1%)
No use, 2018-2019
12.9% (95% CI 10.9%-14.9%)

Inconsistent use of blood pressure-lowering medication · 2005-2006 to 2016-2017

2005-2006
3.9% (95% CI 1.8%-6.0%)
2016-2017
9.0% (95% CI 7.0%-11.0%)
  • Trended upward

Inconsistent use of lipid-lowering medication · 2017-2018

High, 2017-2018
9.9% (95% CI 7.0%-12.7%)
  • Trended up

Original publication

Continuity of Medication Use by US Adults With Diabetes, 2005-2019. JAMA Netw Open. Published 3 January 2023. doi:10.1001/jamanetworkopen.2022.53562

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