Type 2 & other diabetes

National Trends in Out-of-Pocket Cost for Glucose-Lowering Drugs Among U.S. Adults With Diabetes, 2000–2022

Diabetes CarePublished Repeated cross-sectional study

Authors' conclusion

Despite substantial reductions in overall OOP costs, high-cost newer therapies continue to impose financial burdens that may limit equitable access.

Study context

Population
U.S. adults with self-reported diabetes, Medical Expenditure Panel Survey linked to pharmacy-verified records, 2000–2022
Outcome
OOP costs for glucose-lowering medications, per user by medication category and at population level
Follow-up
2000 to 2022
Methodological detailsnationally representative survey, joinpoint regression, inflation-adjusted
  • Nationally representative survey
  • Joinpoint regression
  • Inflation-adjusted

Main finding

As reported in the abstract

Population-average OOP costs

Population-average out-of-pocket (OOP) costs declined

46%

Observational data: associations, not effects.

Further findings

Subgroups (income, race and ethnicity, age, insurance, insulin use, CVD status)

Declines occurred across all subgroups, but differences between subgroups were still observed

Original publication

National Trends in Out-of-Pocket Cost for Glucose-Lowering Drugs Among U.S. Adults With Diabetes, 2000–2022. Diabetes Care. Published 16 June 2026. doi:10.2337/dc25-2040

Composed by AI from the published abstract and checked against it. How Briefs are made →

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