Thyroid disease

Consistency in the Distribution of Bethesda System for Reporting Thyroid Cytology Categories Over 9 Years: A Single Institute, Retrospective Study

Endocr PractPublished Retrospective case series

Authors' conclusion

BSRTC showed consistency throughout the study across all observed categories. An overlap between AUS and benign may exist, possibly due to the heterogenic definition of AUS as reflected in the 2023 BSRTC subclassification for AUS.

Study context

Population
Patients who underwent FNA for a thyroid nodule with a documented Bethesda System for Reporting Thyroid Cytopathology (BSRTC) classification, single institution, 2010–2018
Participants
2,830 thyroid nodules
Outcome
Difference in the rates of BSRTC categories II–VI (benign, AUS, follicular neoplasm, suspicious for malignancy, malignant) between the study years
Follow-up
2010–2018
Methodological detailssingle-centre, chart review
  • Single-centre
  • Chart review

Main finding

As reported in the abstract

Change in BSRTC II–VI category rates across study years (2010–2018)

BSRTC II-VI distribution, respectively

83.9% (2373), 8.2%, (232), 2.7% (75), 3.3% (93), and 2.0% (57)

Observational data: associations, not effects.

Further findings

Benign cytology rate (BSRTC II), 2011 vs 2015 and 2018

Significant change in benign rate between 2011 and 2015 and 2018
P < 0.005

Atypia of undetermined significance (AUS) rate (BSRTC III), 2011 vs 2015 and 2018

Significant change in AUS rate between 2011 and 2015 and 2018
P < 0.005

Original publication

Consistency in the Distribution of Bethesda System for Reporting Thyroid Cytology Categories Over 9 Years: A Single Institute, Retrospective Study. Endocr Pract. Published 2 April 2024. doi:10.1016/j.eprac.2024.03.393

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