Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients
Authors' conclusion
Most pediatric/AYA HSCT recipients have Q-scores indicating suboptimal glycemic control in the peri-HSCT period.
Study context
- Population
- Patients aged 2–30 years admitted inpatient while undergoing hematopoietic stem cell transplant (HSCT) at Children's Hospital Colorado; Continuous glucose monitoring (CGM) (Abbott Freestyle Libre Pro) from up to 7 days before to 60 days after HSCTCGM mean 25 days
- Participants
- 29 patients
- Outcome
- Composite CGM metric Q-score:
- Central tendency
- Hyperglycemia
- Hypoglycemia
- Intradaily
- Interdaily variations
- Follow-up
- Duration of CGM wear
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Q-score · peri-HSCT period
Median Q-score (IQR 8.3, 14.3)
10.2
Patients with Q-scores in the Fair or Poor category
69%
Observational data: associations, not effects.
Further findings
Q-score by clinical factors · peri-HSCT period
- No difference in Q-score by stem cell source, primary disease, preparative regimen, PICU admission, documented infections or TPN use
Original publication
Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients. Diabetes Technol Ther. Published 29 December 2022. doi:10.
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