Comorbidities/cardiovascular risk factors and acute glycaemic emergencies in patients with type 1 and type 2 diabetes: The Australian National Diabetes Audit
Authors' conclusion
Patients with diabetes and comorbidities are more likely to experience acute glycaemic emergencies. Findings assist clinicians identify patients who would benefit from targeted education to reduce glycaemic emergencies.
Study context
- Population
- Adults with diabetes (T1D and T2D), Australian National Diabetes Audit, 2015–2022
- Participants
- 24,492 adults
- Exposure
- Comorbidity/cardiovascular risk factor categories vs no comorbidities/risk factors
- Outcome
- Acute glycaemic emergencies: DKA, HHS and/or severe hypoglycaemia
Methodological detailsmixed effect logistic regression, adjusted analyses
- Mixed effect logistic regression
- Adjusted analyses
Main finding
As reported in the abstract
Acute glycaemic emergencies (adjusted)
Each group vs without comorbidities/risk factorsOdds ratio (95% CI)P value
Discordant comorbidities only
2.28(1.54–3.37)
P < 0.001Concordant comorbidities only
1.53(1.10–2.13)
P = 0.011> 4 comorbiditieshighest odds; dose-dependent relationship with total number of comorbidities
3.71(2.95–4.67)
P < 0.001- Prevalence of acute glycaemic emergencies
- 7.1%
Observational data: associations, not effects.
Original publication
Comorbidities/cardiovascular risk factors and acute glycaemic emergencies in patients with type 1 and type 2 diabetes: The Australian National Diabetes Audit. Diabetes Res Clin Pract. Published 3 April 2026. doi:10. 1016/ j. diabres. 2026. 113241
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