Combined effects of time-restricted eating and exercise on short-term blood glucose management in individuals with Type 2 Diabetes Mellitus: The TREx study, a randomised controlled trial
Authors' conclusion
Post-meal exercise lowered 14-h insulin AUC, neither 8-h TRE nor post-meal exercise altered 14-h blood glucose compared with 12-h eating window. Future work should focus on long-term effects of TRE combined with exercise for enhancing blood glucose in people with type 2 diabetes mellitus.
Study context
- Population
- People with T2D (5 F, 9 M; HbA1c 7.6 ± 1.0%); standardised mealscrossover
- Participants
- 14 people
- Comparison
- Time-restricted eating (TRE) with and without post-meal exercise vs 12-h eating window (CON) with and without exercise
Methodological detailscrossover, Venous blood sampled at 26 timepoints; linear mixed-effects models
- Crossover
- Venous blood sampled at 26 timepoints; linear mixed-effects models
Primary result
As reported in the abstract
Plasma glucose 14-h AUC
- Reducing the eating window had little effect on plasma glucose 14-h AUC
Further findings
- Exercise reduced insulin 14-h AUC, with no additive effect of TRE
- P = 0.01
Original publication
Combined effects of time-restricted eating and exercise on short-term blood glucose management in individuals with Type 2 Diabetes Mellitus: The TREx study, a randomised controlled trial. Diabetes Res Clin Pract. Published 8 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →