Clinicopathological Findings of 220 Pediatric, Adolescent, and Young Adult Patients with Thyroid Cancer in Fukushima Medical University Hospital
Authors' conclusion
The pathological findings of the detected thyroid cancers indicated that the majority were classical papillary carcinomas, and approximately half of the patients had extrathyroidal or lymphovascular invasion. No differences were observed between the two age groups in terms of the clinical or pathological characteristics of thyroid cancer.
Study context
- Population
- Pediatric, adolescent and young adult patients with cytologically diagnosed thyroid cancer referred from the Fukushima Health Management Survey thyroid US examinations, treated at Fukushima Medical University Hospital (as of September 2021)of 263 diagnosed
- Participants
- 220 participants
- Outcome
- Clinicopathological characteristics
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Age at diagnosis, median (IQR)
- 18.6 (16.2-20.3) years
- Maximum tumor diameter, median
- 13.0 (10.4-18.0) mm
- Unilateral lobectomy
- 199 (90.1%)
- Papillary thyroid carcinomas (PTC)
- 216 (98.2%)
- PTC of classical type
- 205
- Stage I disease
- 216 (98.2%)
- Extension into sternothyroid muscle or perithyroidal soft tissues
- 112 (50.9%)
- Microscopic lymphovascular invasion
- 123 (55.9%)
Further findings
Clinical or pathological characteristics by age group (<18.6 years vs ≥18.6 years)
- No differences between the two age groups; risk classification
- P = 0.69
- No differences between the two age groups; ATA pediatric risk level
- P = 0.24
Original publication
Clinicopathological Findings of 220 Pediatric, Adolescent, and Young Adult Patients with Thyroid Cancer in Fukushima Medical University Hospital. Thyroid. Published 14 October 2024. doi:10. 1089/ thy. 2024. 0226
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