Clinical utility of the twiist Automated Insulin Delivery System: first study with twiist
Authors' conclusion
Eight-week use of twiist enabled participants to achieve or maintain established glycemic targets and suggests the system's ability to detect occlusions before clinically significant glucose rise regardless of TDD.
Study context
- Population
- Adults with T1D19 completed
- Participants
- 20 adults
- Outcome
- %TIR (70-180 mg/dL)
- Follow-up
- 8 weeks
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Mean %TIR
70.3±15.5%
Observational data: associations, not effects.
Secondary outcomes
%TIR by correction range
Occlusion events
- Occlusion events, total
- 67
- Participants with occlusion events
- 15
- Events detected within 30 min of rising glucose
Effect of Max basal ratio on %TIR
- Higher max basal ratio settings were associated with higher %TIR
Change in HbA1c, participants with baseline HbA1c >7%
- HbA1c decrease
- −0.4%±0.5%
Change in TDD
- Slight increase in TDD
- 1.3±16.2 U
Change in body weight
- Decrease in body weight
- −0.09±2.9 kg
Safety
- Serious adverse events reported
- 0
Original publication
Clinical utility of the twiist Automated Insulin Delivery System: first study with twiist. BMJ Open Diabetes Res Care. Published 24 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →