Clinical features of type 1 diabetes in older adults and the impact of intermittently scanned continuous glucose monitoring: An Association of British Clinical Diabetologists (ABCD) study
Authors' conclusion
This study demonstrated significant differences in hypoglycaemia awareness and insulin pump use across the older age groups of adults with T1D. The implementation of isCGM demonstrated significant improvements in HbA1c, diabetes-related distress, hypoglycaemia unawareness, and resource utilization in older adults with T1D.
Study context
- Population
- Older adults (≥65 years) with T1D starting intermittently scanned continuous glucose monitoring (isCGM), data submitted by clinicians within the NHS secure network
- Participants
- 1,171 / 374 / 47
- Exposure
- Young-old vs middle-old vs old-old adults with T1D using isCGM
- Young-oldn = 1,171reference
- Middle-oldn = 374
- Old-oldn = 47
- Outcome
- Baseline Gold score (hypoglycaemia awareness)
- Follow-up
- Baseline
Methodological detailsmulticentre, anonymized audit data
- Multicentre
- Anonymized audit data
Main finding
As reported in the abstract
Young-old
3.20
± 1.91
Middle-old
3.46
± 1.94
Old-old
4.05
± 2.28
P < 0.0001
Observational data: associations, not effects.
Further findings
Uptake of insulin pumps and structured education (DAFNE) at baseline
- Reduced insulin pump uptake in middle-old and old-old vs young-old
- P = 0.005
- Reduced DAFNE uptake in middle-old and old-old vs young-old
- P = 0.007
Change in HbA1c with isCGM · median isCGM use 7 months
- Significant HbA1c improvement in young-old
- P < 0.001
- Significant HbA1c improvement in old-old; not in middle-old
Change in Diabetes Distress Scale (DDS2) score with isCGM · median isCGM use 7 months
- DDS2 improved in all three age groups
- P < 0.001
Change in Gold score with isCGM · median isCGM use 7 months
- Gold score improved in young-old and old-old, not in middle-old
- P < 0.001
Resource utilization · following isCGM use
- Significant improvement in resource utilization across the three age categories
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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