Thyroid disease

Clinical factors influencing the success rate of radioiodine treatment for Graves' disease

Diabetes Obes MetabPublished Retrospective cohort study

Authors' conclusion

We found that female patients and those with TRAbs ≥31.83 IU/L and thyroid mass ≥ 73.42 g had a lower cure rate. Therefore, thyroid size, disease severity, and duration of disease should be comprehensively considered when making treatment decisions and iodine dose selection in clinical practice.

Study context

Population
Patients with GD treated with RAI at the Second Affiliated Hospital of Anhui Medical University, October 2012–October 2022; 594 (29.8%) male, 1399 (70.2%) female
Participants
1,994 patients
Exposure
Success vs Failure
  • Successn = 1,645
  • Failuren = 349reference
Outcome
Success rate of RAI therapy for GD and factors associated with success
Follow-up
Within 3 years
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

RAI treatment success · 3-year follow-up

Observational data: associations, not effects.

Original publication

Clinical factors influencing the success rate of radioiodine treatment for Graves' disease. Diabetes Obes Metab. Published 18 July 2024. doi:10.1111/dom.15790

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