Endocrine oncology

Clinical factors for choosing active surveillance: an analysis of papillary thyroid microcarcinoma patients with recurrence

Eur Thyroid JPublished Retrospective cohort study

Authors' conclusion

When choosing between surgical treatment or AS in PTMC patients, additional consideration of the patient's clinical factors, such as age and BRAF mutation status, may be required in addition to the existing criteria.

Study context

Population
Patients with papillary thyroid microcarcinoma (PTMC) who underwent surgical treatment at Chungnam National University Hospital
Participants
2,717 patients
Exposure
Recurrence vs no recurrence after surgery for PTMC
  • Recurrencen = 60
Outcome
Preoperatively identifiable clinical factors related to recurrence
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

  • BRAF mutation and tall cell variant significantly more common in patients with recurrence
  • Age ≥55 years: lower risk of recurrence than younger patients and higher recurrence-free survival rate

Observational data: associations, not effects.

Original publication

Clinical factors for choosing active surveillance: an analysis of papillary thyroid microcarcinoma patients with recurrence. Eur Thyroid J. Published 28 December 2023. doi:10.1530/etj-23-0195

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