Gestational diabetes & diabetes in pregnancy

Clinical Effectiveness of Continuous Glucose Monitoring in Pregnancies Affected by Type 1 Diabetes

Diabetes Technol TherPublished Retrospective cohort study

Authors' conclusion

CGM use was associated with improved maternal glucose levels in a diverse real-world cohort.

Study context

Population
T1D pregnancies at the Barbara Davis Center for Diabetes, 2014–2020; obstetric care at multiple practices (Colorado and Wyoming)T1D pregnancies
Participants
160 pregnancies
Exposure
Continuous glucose monitoring (CGM) vs self-monitoring of blood glucose (SMBG)
  • CGMn = 109
  • SMBGn = 51reference
Outcome
Maternal glucose control and gestational health outcomes
Methodological detailsreal-world setting, single-centre, Data from electronic medical records, hospital records and vital statistics departments; Student's t-test and chi-square test
  • Real-world setting
  • Single-centre
  • Data from electronic medical records, hospital records and vital statistics departments; Student's t-test and chi-square test

Main finding

As reported in the abstract

Meeting trimester-specific HbA1c goals · throughout pregnancy and postpartum
  • More participants meeting trimester-specific hemoglobin A1C (HbA1c) goals in CGM group
  • CGM vs SMBG: P < 0.01 in each time period

Observational data: associations, not effects.

Further findings

Macrosomia

P = 0.01

Neonatal ICU admission

P = 0.0989

Never meeting HbA1c goals in any trimester · fewer with CGM
P < 0.001

Other neonatal outcomes

No significant differences in neonatal outcomes between groups, other than macrosomia

Original publication

Clinical Effectiveness of Continuous Glucose Monitoring in Pregnancies Affected by Type 1 Diabetes. Diabetes Technol Ther. Published 25 March 2024. doi:10.1089/dia.2023.0548

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