Osteoporosis, bone & mineral

Clinical characteristics of pregnancy and lactation associated osteoporosis: An online survey study

Osteoporos IntPublished Cross-sectional study

Authors' conclusion

The large number of participants and broad range of clinical and fracture characteristics queried has yielded novel information on the characteristics of PLO and potential risk factors for its severity, including primiparity, exposure to heparin and CD.

Study context

Population
Patients with pregnancy and lactation associated osteoporosis (PLO)
Participants
177 completed surveys
Outcome
Disease severity: total number of fractures during or after the first pregnancy associated with a fracture(s), related to potential predictors
Methodological detailsanonymized online questionnaire, Surveys received between 5/29/2018 and 1/12/2022
  • Anonymized online questionnaire
  • Surveys received between 5/29/2018 and 1/12/2022

Main finding

As reported in the abstract

Age at initial PLO fracture event, average
32 ± 5 years
Fractured during lactation
79%
Total PLO fractures
4.7 ± 2.7
Reporting ≥ 5 fractures
48%
Vertebral fractures (most common fracture type)
164/177 (93%)

Observational data: associations, not effects.

Original publication

Clinical characteristics of pregnancy and lactation associated osteoporosis: An online survey study. Osteoporos Int. Published 19 May 2023. doi:10.1007/s00198-023-06793-9

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