Clinical characteristics of pregnancy and lactation associated osteoporosis: An online survey study
Authors' conclusion
The large number of participants and broad range of clinical and fracture characteristics queried has yielded novel information on the characteristics of PLO and potential risk factors for its severity, including primiparity, exposure to heparin and CD.
Study context
- Population
- Patients with pregnancy and lactation associated osteoporosis (PLO)
- Participants
- 177 completed surveys
- Outcome
- Disease severity: total number of fractures during or after the first pregnancy associated with a fracture(s), related to potential predictors
Methodological detailsanonymized online questionnaire, Surveys received between 5/29/2018 and 1/12/2022
- Anonymized online questionnaire
- Surveys received between 5/29/2018 and 1/12/2022
Main finding
As reported in the abstract
- Age at initial PLO fracture event, average
- 32 ± 5 years
- Fractured during lactation
- 79%
- Total PLO fractures
- 4.7 ± 2.7
- Reporting ≥ 5 fractures
- 48%
- Vertebral fractures (most common fracture type)
- 164/177 (93%)
Observational data: associations, not effects.
Original publication
Clinical characteristics of pregnancy and lactation associated osteoporosis: An online survey study. Osteoporos Int. Published 19 May 2023. doi:10. 1007/ s00198-023-06793-9
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