Obesity

Classification of childhood obesity using longitudinal clinical body mass index and its validation

Int J Obes (Lond)Published Observational cohort study

Authors' conclusion

The Longitudinal BMI classification may better reflect long-term cardiometabolic risk in children. This classification can be useful for focused intervention strategies and for profiling of individuals for genetic testing.

Study context

Population
Children with height, weight and cardiometabolic risk measures, tertiary care hospital EHR 2014–18; replication in an independent cohort24,444 in replication cohort
Participants
22,352 children
Exposure
Longitudinal body mass index (BMI) classification vs cross-sectional BMI
Outcome
AUC for cardiometabolic risk
Methodological detailselectronic health record data, tertiary care hospital, independent replication cohort
  • Electronic health record data
  • Tertiary care hospital
  • Independent replication cohort

Main finding

As reported in the abstract

GroupValueAUC
Longitudinal BMI class80.0%80.0%
Cross-sectional BMI75.8%75.8%

Value

Longitudinal BMI class80.0%
Cross-sectional BMI75.8%

AUC

Longitudinal BMI class80.0%
Cross-sectional BMI75.8%
  • Longitudinal BMI class vs Cross-sectional BMI: P < 0.001 — AUC higher with longitudinal BMI class

Observational data: associations, not effects.

Further findings

Prevalence of obesity (BMI ≥ 95th percentile) and severe obesity (BMI ≥ 120% of BMIpct95)

Obesity
24.1%
Severe obesity
10.6%

Early onset obesity (age ≤ 6 years)

Individuals with early onset obesity remained in the same or higher obesity class

Socioeconomic status (SES) and obesity

High-SES group had lower odds of obesity

Proportion with cardiometabolic risk by obesity severity

Proportion with cardiometabolic risk increased with obesity severity
p-value 0.01 - < 0.001

Original publication

Classification of childhood obesity using longitudinal clinical body mass index and its validation. Int J Obes (Lond). Published 17 July 2025. doi:10.1038/s41366-025-01836-z

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