Childhood BMI trajectories predict cardiometabolic risk and perceived stress at age 13 years: the STARS cohort
Authors' conclusion
An excessive gain BMI trajectory from birth predicts cardiometabolic risk and stress in 13-year-old individuals.
Study context
- Population
- Adolescents aged 13 years in the STARS cohort, 44% male; BMI trajectories from birth throughout childhood
- Participants
- 1,902 adolescents
- Exposure
- Excessive gain and moderate gain BMI trajectories vs normal gain
- Outcome
- Health outcomes at age 13 years (adjusted estimated mean differences)
- Follow-up
- Age 13 years
Methodological detailsgroup-based trajectory modeling, retrospective weight/height data
- Group-based trajectory modeling
- Retrospective weight/height data
Main finding
As reported in the abstract
Each group vs normalEstimated mean difference (WC), cm (95% CI)
Excessive gain
19.2(18.4–20.0)
Moderatehigher with moderate gain
6.4(5.8–6.9)
Each group vs normalEstimated mean difference (SBP), mm Hg (95% CI)
Excessive gain
3.6(2.4–4.4)
Moderatehigher with moderate gain
1.8(1.0–2.5)
Each group vs normalEstimated mean difference (WBC), × 109 /L (95% CI)
Excessive gain
0.7(0.4–0.9)
Each group vs normalEstimated mean difference (stress) (95% CI)
Excessive gain
1.1(0.2–1.9)
Moderatehigher with moderate gain
0.7(0.1–1.2)
Observational data: associations, not effects.
Further findings
Timing of association of early-life BMI with systolic blood pressure (SBP)
- Association started around age 6 years with excessive gain
- Association started at age 12 years with normal and moderate gain
Original publication
Childhood BMI trajectories predict cardiometabolic risk and perceived stress at age 13 years: the STARS cohort. Obesity (Silver Spring). Published 19 December 2023. doi:10.
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