Diabetes complications

Charcot Foot Offloading in Stage 0 Is Associated With Shorter Total Contact Cast Treatment and Lower Risk of Recurrence and Reconstructive Surgery: A Pilot Study

Diabetes CarePublished Retrospective cohort study

Authors' conclusion

Offloading in stage 0 CF was associated with shorter TCC treatment, lower risk of a new CF event, and diminished need for reconstructive surgery. Future amputation risk was not affected.

Study context

Population
Patients treated for active Charcot foot at Skåne University Hospital (Lund, Sweden), 2006–2019; median age 61 years, 37% T1D, 62% men183 individuals
Participants
198 analyzed charcot foot (CF) events
Exposure
Offloading in stage 0 vs offloading in stage 1 Charcot foot
  • Stage 0n = 74
  • Stage 1n = 124reference
Outcome
Duration of total contact casting (TCC)
Methodological detailssingle-centre, pilot study, Median follow-up 7.0 (IQR 3.9-11) years
  • Single-centre
  • Pilot study
  • Median follow-up 7.0 (IQR 3.9-11) years

Main finding

As reported in the abstract

TCC duration

P = 0.001

Observational data: associations, not effects.

Further findings

New ipsilateral CF events >1 year after definitive footwear

P < 0.05

OutcomeStage 0Stage 1P value
Reconstructive surgery0 events8.9%P < 0.01

Amputation

Amputation rates were similar

Original publication

Charcot Foot Offloading in Stage 0 Is Associated With Shorter Total Contact Cast Treatment and Lower Risk of Recurrence and Reconstructive Surgery: A Pilot Study. Diabetes Care. Published 30 November 2023. doi:10.2337/dc23-1063

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