Diabetes complications

Grading Fractures on Foot and Ankle X-rays and MRI Scans in the Active Charcot Foot in Diabetes: How Strong Is the Agreement Between Modalities?

Diabetes CarePublished Diagnostic accuracy study

Authors' conclusion

The significant underperformance of X-ray in the assessment of the hot, swollen foot in diabetes should be considered when confirming or refuting the diagnosis of active CNO.

Study context

Population
People with diabetes and active Charcot neuro-osteoarthropathy (CNO)
Participants
48 people
Comparison
X-ray vs MRI for grading fractures and detecting bone injury in active CNO
Outcome
Agreement between X-ray and MRI (tests for symmetry, marginal homogeneity, κ-coefficients)

Performance

As reported in the abstract

Κ (fracture severity grading)

0.53

P < 0.001

moderate to substantial agreement

Κ (detecting bone injury)

0.17

P < 0.001

slight to fair agreement

X-ray underscored MRI in grading fractures in the metatarsals
P = 0.05
X-ray underscored MRI in grading fractures in the tarsals
P < 0.001
Bones with bone marrow edema (BME) reported as normal on X-ray
79%

Original publication

Grading Fractures on Foot and Ankle X-rays and MRI Scans in the Active Charcot Foot in Diabetes: How Strong Is the Agreement Between Modalities? Diabetes Care. Published 12 July 2023. doi:10.2337/dc23-0220

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