Cardiovascular risk stratification in an ethnically mixed population with type 1 diabetes mellitus: comparison of the Steno Type 1 Risk Engine with the Scottish-Swedish risk model
Authors' conclusion
In this ethnically mixed and predominantly young T1D cohort, both the ST1RE and the Scottish-Swedish models demonstrated good discriminative ability and calibration for 10-year CV risk prediction.
Study context
- Population
- Adults with T1D and no prior cardiovascular disease (CVD); predominantly young, ethnically diverse; median age 25 years (IQR: 21–32), T1D duration 13 years (IQR: 9–18)
- Participants
- 435 adults
- Exposure
- Steno Type 1 Risk Engine vs Scottish-Swedish risk model
- Outcome
- Performance of the models in predicting 10-year CV events:
- Kaplan-Meier
- ROC curves
- Hosmer-Lemeshow test
- Cohen's kappa
- Follow-up
- 10-year
Methodological detailsrisk model comparison
- Risk model comparison
Main finding
As reported in the abstract
follow-up 9.2 years
CV events
24 participants
5.5 %
Observational data: associations, not effects.
Further findings
Risk classification: low risk
Risk classification: moderate risk
Risk classification: high risk
Agreement between the models
- Moderate agreement between the models, κ
- 0.550 (95% CI 0.468-0.632)
Original publication
Cardiovascular risk stratification in an ethnically mixed population with type 1 diabetes mellitus: comparison of the Steno Type 1 Risk Engine with the Scottish-Swedish risk model. Diabetes Res Clin Pract. Published 24 July 2025. doi:10.
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