Cardiac arrhythmia and hypoglycaemia among individuals with and without diabetes receiving haemodialysis (the CADDY study): a Danish multicentre cohort study
Authors' conclusion
Arrhythmias and hypoglycaemia were common in those undergoing haemodialysis regardless of diabetes status. Our data suggest a temporal relationship between arrhythmias and glucose level in both individuals with and without diabetes.
Study context
- Population
- Individuals on maintenance haemodialysis, Danish multicentre
- Participants
- 70 individuals
- Exposure
- Individuals with diabetes vs without diabetes on haemodialysis
- Diabetesn = 35
- Without diabetesn = 35reference
- Outcome
- Clinically significant arrhythmias (bradyarrhythmia and ventricular tachycardia)
- Follow-up
- 18 months
Methodological detailsmulticentre, implantable cardiac monitors, periodic CGM
- Multicentre
- Implantable cardiac monitors
- Periodic CGM
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
AF · 18 months of follow-up
Other supraventricular tachycardia · 18 months of follow-up
Hypoglycaemia (sensor glucose <3.9 mmol/l) · 18 months of follow-up
| Outcome | IRR (95% CI) | |
|---|---|---|
| Arrhythmia rate with hypoglycaemiavs euglycaemia, participants without diabetesWithout diabetes | 3.13 (1.49–6.55) | |
| Arrhythmia rate with hyperglycaemia (sensor glucose >10.0 mmol/l)vs euglycaemia, participants with diabetesDiabetes | 0.58 (0.37–0.92) | |
| 0.10.31310Incidence rate ratio (log scale) |
Glycaemic variability and arrhythmias
- Glycaemic variability showed no association with arrhythmias regardless of diabetes
Original publication
Cardiac arrhythmia and hypoglycaemia among individuals with and without diabetes receiving haemodialysis (the CADDY study): a Danish multicentre cohort study. Diabetologia. Published 28 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →