Breast satisfaction in adult women with Turner syndrome—An international survey employing the BREAST‐Q questionnaire
Authors' conclusion
TS women who received oestrogen replacement for pubertal induction self-report lower breast satisfaction scores and late menarche, suggesting that type, mode of delivery, dose and timing of hormone supplements merit prospective study.
Study context
- Population
- Adult women aged 18–45 years with self-reported turner syndrome (TS), recruited online through TS support groups; median age 32 years, 97% White Caucasian, 86% had pubertal induction therapy74 matched
- Participants
- 97 women
- Exposure
- Women with TS vs matched normative controls
- TSn = 74
- Outcome
- BREAST-Q scores (four domains), incl. 'Satisfaction with Breast'
Methodological detailsinternational online survey, matched on age, body mass index (BMI) and educational background to normative data
- International online survey
- Matched on age, BMI and educational background to normative data
Main finding
As reported in the abstract
BREAST-Q scores
- TS vs Army of Women: P = 0.021
- TS vs Army of Women: P < 0.0001
- TS vs Army of Women: P < 0.0001
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| BREAST-Q scores by oestrogen replacement therapy in TSOestrogen therapy vs No oestrogen therapy · lower scores with oestrogen therapy | P < 0.0001 |
Factors associated with breast satisfaction
- Lower BMI and previous GH therapy were associated with lower breast satisfaction
Age at menarche and pubertal induction
- Median age at menarche
- 15.5 years (12-34 years)
- Received pubertal induction therapy as teenagers
- 86%
Original publication
Breast satisfaction in adult women with Turner syndrome—An international survey employing the BREAST‐Q questionnaire. Clin Endocrinol (Oxf). Published 25 May 2022. doi:10.
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