Body weight, weight change and the risk of cardiovascular disease in patients with hypertension: a primary-care cohort study
Authors' conclusion
Obesity and weight change of loss ≥4% and gain >4% were related to higher risks of CVD. Close monitoring and appropriate interventions aimed at achieving an optimal weight are needed to prevent adverse cardiovascular outcomes for patients with hypertension.
Study context
- Population
- Patients with hypertension with valid weight measurements attending primary healthcare centers, China
- Participants
- 24,750 patients
- Exposure
- BMI categories and 12-month weight change categories vs reference
- Outcome
- Risk of cardiovascular disease (CVD)
Methodological detailsprimary-care medical records, multivariable-adjusted Cox regression
- Primary-care medical records
- Multivariable-adjusted Cox regression
Main finding
As reported in the abstract
CVD
Hazard ratio (95% CI)
Obesity
1.48(1.19–1.85)
Loss ≥4%vs Stable
1.33(1.04–1.70)
Gain >4%vs Stable
1.36(1.04–1.77)
Observational data: associations, not effects.
Original publication
Body weight, weight change and the risk of cardiovascular disease in patients with hypertension: a primary-care cohort study. Int J Obes (Lond). Published 6 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →