Body mass index and the risk of ulnar nerve entrapment in individuals without diabetes—a longitudinal cohort study from Sweden
Authors' conclusion
High BMI is associated with the development of UNE in individuals without diabetes, indicating that high BMI is an independent risk factor for the development of nerve entrapment disorders irrespective of hyperglycaemia.
Study context
- Population
- Individuals without prevalent or incident diabetes mellitus (DM) recruited to the Malmö Diet and Cancer Study 1991–1996, Sweden; followed to ulnar nerve entrapment (UNE) diagnosis, emigration, death or December 31, 202030,446 recruited
- Participants
- 23,254 individuals
- Exposure
- Overweight and obesity vs normal weight
- Outcome
- Incident ulnar nerve entrapment (UNE)
- Follow-up
- Over 25 years
Methodological detailslongitudinal, Malmö Diet and Cancer Study cross-linked with Swedish Patient Register, Cox models adjusted for age, sex, hypertension, smoking, manual work and alcohol consumption
- Longitudinal
- Malmö Diet and Cancer Study cross-linked with Swedish Patient Register
- Cox models adjusted for age, sex, hypertension, smoking, manual work and alcohol consumption
Main finding
As reported in the abstract
Incident UNE · follow-up over 25 years
Hazard ratio (95% CI)P value
BMImultivariable Cox regression; BMI independently associated with UNE
1.07(1.03–1.11)
P < 0.001Overweightvs Normal weight
1.55(1.12–2.15)
P < 0.01Obesityvs Normal weight
2.23(1.40–3.57)
P = 0.001Observational data: associations, not effects.
Original publication
Body mass index and the risk of ulnar nerve entrapment in individuals without diabetes—a longitudinal cohort study from Sweden. Int J Obes (Lond). Published 17 September 2025. doi:10.
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