Body mass index across development and adolescent hair cortisol: the role of persistence, variability, and timing of exposure
Authors' conclusion
This study strengthens empirical support for BMI-HCC association and suggests that more attention should be devoted to BMI fluctuations in addition to persistent trajectories of BMI.
Study context
- Population
- Youth with body mass index (BMI) measured prospectively at twelve occasions between age 5 months and 15 years; hair sampled at age 17565 with hair sampled
- Participants
- 946 / 507 / 128
- Exposure
- BMI trajectories vs low-stable
- Low-stablen = 946reference
- Moderaten = 507
- High-risingn = 128
- Outcome
- Hair cortisol concentration (HCC)
- Follow-up
- Age 17
Methodological detailslongitudinal, latent class analysis
- Longitudinal
- Latent class analysis
Main finding
As reported in the abstract
HCC by BMI trajectory
β
0.10
95% CI 0.02–0.40P = 0.03
Moderate · higher hair cortisol concentration (HCC) with moderate
β
−0.02
95% CI −0.47–0.32P = 0.71
High-rising · association not detected
Observational data: associations, not effects.
Further findings
BMI variability across development and HCC
- Higher BMI variability predicted higher cortisol (β), additively to BMI trajectories
- 0.17 (95% CI 0.10-4.91; p = 0.003)
- BMI variability in childhood was responsible for that finding, possibly suggesting a timing effect
Original publication
Body mass index across development and adolescent hair cortisol: the role of persistence, variability, and timing of exposure. Int J Obes (Lond). Published 4 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →