BMI at different childhood age periods associated with cardiometabolic disorders in young adulthood
Authors' conclusion
The association between childhood BMI and adult cardiometabolic disorders begins to be operative from early life. These results support universal screening of childhood obesity starting at an early age.
Study context
- Population
- Participants with adult data on blood pressure, lipid profile, fasting blood glucose, fasting insulin or alanine aminotransferase and ≥1 childhood BMI measurement
- Participants
- 811 participants
- Exposure
- Childhood BMI z score at ages 6–9, 10–12, 13–15 and 16–18 years and adult cardiometabolic disorders
- Outcome
- Cardiometabolic disorders in adulthood
- Follow-up
- Young adulthood
Main finding
As reported in the abstract
≥1 and ≥2 cardiometabolic disorders and elevated blood pressure in adulthood
- Childhood BMI z score significantly associated with increased risks of ≥1 and ≥2 cardiometabolic disorders and elevated blood pressure for age groups 6–9, 10–12, 13–15 and 16–18 years
- After adjustment for covariates
Observational data: associations, not effects.
Further findings
Low HDL-C
- Significant associations for age groups 10–12, 13–15 and 16–18 years
Elevated TG and elevated alanine aminotransferase
- Significant associations for age groups 13–15 and 16–18 years
Insulin resistance
- Significant associations for age groups 10–12 and 16–18 years
Elevated total cholesterol, LDL-C or fasting blood glucose
- No association in any age group
Original publication
BMI at different childhood age periods associated with cardiometabolic disorders in young adulthood. Obesity (Silver Spring). Published 8 August 2023. doi:10.
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