Bereavement and type 1 diabetes in childhood: a register-based cohort study in Sweden
Main finding · T1D in childhood (<18 years)Result — go to the resultAdjusted hazard ratio 1.04 95% CI 0.93–1.17Authors' conclusion
In this large population-based Swedish study, we observed no evidence supporting a link between childhood bereavement and type 1 diabetes.
Study context
- Population
- Children born in Sweden between 1987 and 2020
- Participants
- 3,598,159 children
- Exposure
- Childhood bereavement vs no bereavement
- Childhood bereavementn = 86,226
- Outcome
- T1D diagnosed in childhood (<18 years), National Patient Register
Methodological detailspopulation-based, Cox proportional hazards regression, adjusted for parental T1D status, country of birth and demographic characteristics
- Population-based
- Cox proportional hazards regression
- Adjusted for parental T1D status, country of birth and demographic characteristics
Main finding
T1D in childhood (<18 years)
Adjusted hazard ratio
1.04
95% CI 0.93–1.17
Childhood bereavementvs No bereavement
aHR 1.04 (95% CI 0.93–1.17)
As reported in the abstract
Observational data: associations, not effects.
Further findings
T1D incidence (whole cohort)
- Children diagnosed with T1D
- 18,817 (0.52%)
- Median age at onset
- 9.1 years
Bereavement characteristics
- No influence of age at loss, cause of death, familial relationship to the deceased, and time since loss
Original publication
Bereavement and type 1 diabetes in childhood: a register-based cohort study in Sweden. Diabetologia. Published 19 December 2024. doi:10. 1007/ s00125-024-06340-z
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