Beneficial Effects of RESMENA Diet on Anthropometric, Metabolic, and Reproductive Profile in Adolescents with Obesity and Polycystic Ovary Syndrome: A Randomized Controlled Intervention Study
Authors' conclusion
Both dietary patterns resulted in significant improvement in anthropometric measurements and body composition, but the RESMENA diet showed beneficial effects on insulin resistance parameters and androgen levels.
Study context
- Population
- Adolescents aged 13–18 years with polycystic ovary syndrome (PCOS) (and obesity)
- Participants
- 40 adolescents
- Comparison
- RESMENA diet vs control diet based on American Heart Association (AHA) recommendations
Primary result
As reported in the abstract
Anthropometric parameters · 6 months
- Both diets significantly decreased anthropometric parameters; RESMENA gave a greater decrease in all except neck circumference and fat percentage
- p <0.05
Further findings
Metabolic parameters · end of study
- HbA1c, HOMA-IR and hs-CRP decreased and QUICKI score increased in RESMENA
- P < 0.05
- Fasting insulin, ALT and total cholesterol decreased in both groups
Androgen and reproductive hormones · end of study
- RESMENA: significant decrease in total and free testosterone, 17-OH progesterone, androstenedione, LH, LH/FSH ratio and free androgen index; significant increase in SHBG
- P < 0.05
- No statistical difference in androgen levels vs baseline in control
Original publication
Beneficial Effects of RESMENA Diet on Anthropometric, Metabolic, and Reproductive Profile in Adolescents with Obesity and Polycystic Ovary Syndrome: A Randomized Controlled Intervention Study. Horm Res Paediatr. Published 10 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →