Neck circumference as a metabolic health marker among women with polycystic ovary syndrome (PCOS): a systematic review and meta-analysis
Pooled result · Neck circumferenceResult — go to the resultSMD 0.78 95% CI 0.31–1.25Authors' conclusion
This meta-analysis demonstrated increased NC among women with PCOS compared to healthy controls. Women with PCOS and larger NC were more insulin resistant and had more MetS-related abnormalities when compared to women with smaller NC with or without PCOS. Data considering NC cut-off values for MetS and IR among women with PCOS are scarce, and further studies are needed, particularly among more varied ethnic populations.
Study context
- Population
- Women with PCOS; studies of neck circumference (NC) and anthropometric measurements, blood pressure (BP), lipids, glucose metabolism, metabolic syndrome (MetS) or insulin resistance (IR) (PubMed/Medline and Scopus)13 studies
- Comparison
- Women with PCOS vs non-PCOS controls
- Outcome
- NC values in women with PCOS vs non-PCOS controls
Pooled result
Neck circumference
SMD
0.78
95% CI 0.31–1.25
P = 0.0012
PCOSvs Non-PCOS controls
SMD 0.78 (95% CI 0.31–1.25); P = 0.0012
As reported in the abstract
Further pooled results
Associations of NC with metabolic markers
- Larger NC associated with higher waist and hip circumference, TG, systolic BP, fasting insulin and HOMA-IR or lower HOMA%S, and higher prevalence of MetS or IR in the majority of included studies
NC cut-off values among women with PCOS
- Cut-off for MetS
- 33 cm to 34.25 cm
- Cut-off for IR
- 34.25 cm up to 42 cm
- Most studies in Asian populations
Original publication
Neck circumference as a metabolic health marker among women with polycystic ovary syndrome (PCOS): a systematic review and meta-analysis. Int J Obes (Lond). Published 21 April 2025. doi:10.
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